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Natalie D Eddington Selected Research

Benztropine (Benzatropine)

12/2008The novel N-substituted benztropine analog GA2-50 possesses pharmacokinetic and pharmacodynamic profiles favorable for a candidate substitute medication for cocaine abuse.
5/2008Population pharmacokinetics, brain distribution, and pharmacodynamics of 2nd generation dopamine transporter selective benztropine analogs developed as potential substitute therapeutics for treatment of cocaine abuse.
1/2007Transport, metabolism, and in vivo population pharmacokinetics of the chloro benztropine analogs, a class of compounds extensively evaluated in animal models of drug abuse.
7/2006Investigation of the potential pharmacokinetic and pharmaco-dynamic drug interaction between AHN 1-055, a potent benztropine analog used for cocaine abuse, and cocaine after dosing in rats using intracerebral microdialysis.

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Natalie D Eddington Research Topics

Disease

6Cocaine-Related Disorders (Cocaine Addiction)
12/2008 - 03/2002
4Body Weight (Weight, Body)
01/2015 - 12/2003
4Substance-Related Disorders (Drug Abuse)
06/2010 - 01/2007
2Bronchopulmonary Dysplasia
05/2013 - 09/2011
2Opioid-Related Disorders (Opiate Addiction)
12/2010 - 12/2009
2Mitochondrial Diseases (Mitochondrial Disease)
08/2010 - 09/2008
2Drug-Related Side Effects and Adverse Reactions
10/2008 - 05/2003
1Ureaplasma Infections (Ureaplasma Infection)
09/2011
1Heroin Dependence (Heroin Abuse)
09/2009
1Pain (Aches)
06/2009
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
12/2008
1Hemorrhage
10/2008
1Heart Failure
06/2007
1Hypertension (High Blood Pressure)
06/2007
1Chronic Kidney Failure (Chronic Renal Failure)
05/2003
1Renal Insufficiency (Renal Failure)
05/2003
1Breast Neoplasms (Breast Cancer)
09/2002

Drug/Important Bio-Agent (IBA)

4Benztropine (Benzatropine)FDA LinkGeneric
12/2008 - 07/2006
3Azithromycin (Zithromax)FDA LinkGeneric
01/2015 - 09/2011
3Methadone (Dolophine)FDA LinkGeneric
12/2010 - 09/2009
2Buprenorphine (Subutex)FDA LinkGeneric
12/2010 - 12/2009
2N-Methyl-3,4-methylenedioxyamphetamine (MDMA)IBA
08/2010 - 09/2008
2Mitochondrial Proteins (Mitochondrial Protein)IBA
08/2010 - 09/2008
2Pharmaceutical PreparationsIBA
12/2009 - 05/2003
2EnzymesIBA
09/2008 - 05/2003
2Cocaine (Cocaine HCl)IBA
05/2008 - 07/2006
2Dopamine (Intropin)FDA LinkGeneric
08/2007 - 04/2005
1Biological ProductsIBA
09/2011
1Opioid Receptors (Opioid Receptor)IBA
12/2010
1Dopamine D3 ReceptorsIBA
06/2010
1DiprenorphineIBA
12/2009
1Opioid Analgesics (Opioids)IBA
06/2009
16-desoxymorphineIBA
06/2009
1Surface-Active Agents (Surfactants)IBA
12/2008
1Transaminases (Aminotransferases)IBA
10/2008
1odiparcilIBA
10/2008
1Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
05/2008
1Carvedilol (Coreg)FDA LinkGeneric
06/2007
1Dihydrotachysterol (AT 10)IBA
12/2003
1CytochromesIBA
05/2003
1Erythromycin (Erycette)FDA LinkGeneric
05/2003
1Rifampin (Rifampicin)FDA LinkGeneric
05/2003
1Cytochrome P-450 CYP3AIBA
05/2003
1Doxorubicin (Adriamycin)FDA LinkGeneric
09/2002
1Anticonvulsants (Antiepileptic Drugs)IBA
09/2002
1TropanesIBA
03/2002

Therapy/Procedure

3Therapeutics
05/2008 - 03/2002
2Drug Therapy (Chemotherapy)
09/2009 - 04/2005